In older people, this is essential to understand as polypharmacy is prevalent and will potentiate the potential risk of DDIs and ADRs. Therefore, concurrent ingestion of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and this could enhance or lessen efficacy/ADRs in the prescribed tramadol. https://lutherm510hyo2.mysticwiki.com/user