Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but they are uncommon in this malignancy as compared to other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and 7% of MBL.75 The histone methyltransferase SETD2 and ARID1A are also mutated in a small proportion https://dukep520hpw7.wikicommunication.com/user