2. Histamine Receptor Antagonism: Some sedatives, like antihistamines, exert their sedative effects by blocking histamine receptors while in the brain, notably H1 receptors. Histamine plays a role in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness. Opioids are especially susceptible to getting to be addictive and https://sedativesdrugs08641.59bloggers.com/33498061/popular-sedative-drug-names-medical-purposes-side-effects