Pentobarbital will reduce the extent or result of artemether/lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration with strong CYP3A4 inducers can lead to diminished serum concentrations and loss of antimalarial efficacy pentobarbital will lessen the extent or effect of diltiazem by affecting hepatic/intestinal https://pennr482qyh7.wikicorrespondent.com/user