Conolidine’s analgesic outcomes stem from its conversation with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors inside the central anxious process, conolidine modulates alternate molecular targets. A Science Innovations analyze discovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availa... https://isconolidinearealpainreli53074.canariblogs.com/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers-52899637